Prof. MD.
İbrahim Toprak
Liv Hospital Ulus
Ophthalmology
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Areas of Interests
- Keratoconus (thinning and protrusion of the cornea) and corneal ectasia: early diagnosis and treatment
- Cross-linking treatment (CXL)
- Personalized CXL protocol for ultra-thin corneas
- Cretan and Athens protocols (combined laser and CXL treatments)
- Intracorneal ring (ICRS) applications, with femtosecond laser
- Keratoconus in children and adolescents
- Post-laser ectasia (corneal thinning after laser surgery)
- Evaluation and treatment of vision problems after laser surgery
- Corneal transplantation (keratoplasty)
- Detailed suitability assessment before laser surgery and detection of at-risk eyes
- Reducing the need for glasses with laser (myopia, astigmatism, hyperopia): No-Touch PRK, PRK, Femto-LASIK (i-LASIK)
- Phaki lens (intraocular contact lens), for high prescriptions and eyes unsuitable for laser
- Cataract surgery (FAKO, sutureless)
- Smart lenses (multifocal, EDOF, toric): personalized suitability analysis and lens selection
- Glaucoma (eye pressure): diagnosis, follow-up, medication and laser treatment
- Glaucoma surgery (trabeculectomy, Ahmed glaucoma valve implantation)
- Corneal diseases (corneal ulcers and infections)
- Dry eye and eye allergies
- Eye surface diseases (stem cell failure, eye surface infections and tumors)
- Pterygium (tissue progressing towards the pupil) surgery
47
International Articles
16
h-index
EDUCATION INFORMATION
- 1998–2004: Dokuz Eylül University Faculty of Medicine–Faculty of Medicine
- 2004–2010: Pamukkale University Faculty of Medicine–Ophthalmology Specialization Training
- 2019: Vissum Instituto Oftalmológico, Alicante, Spain–Prof. Dr. Jorge L. Alió Corneal, Cataract and Refractive Surgery Fellowship
- 2023: Ospedale Privati Forli, Italy – Corneal Surgery with Prof. Dr. Massimo Busin
- 2024: St. Franziskus Hospital Münster, Germany – Refractive Surgery with Prof. Dr. Suphi Taneri
ACADEMIC EXPERIENCE
- 2026: Pamukkale University Faculty of Medicine, Ophthalmology – Head of Department
- 2025–2026: Pamukkale University Faculty of Medicine – Professor
- 2019–2025: Pamukkale University Faculty of Medicine – Associate Professor
- 2017–2019: Pamukkale University Faculty of Medicine – Dr. Öğr. Member
PROFESSIONAL EXPERIENCE
- 2026–Present: Liv Hospital Ulus – Ophthalmology Specialist / Professor
- 2017–2026: Pamukkale University Faculty of Medicine Hospital – Ophthalmology Faculty Member / Head of Department
- 2019: Vissum Instituto Oftalmológico, Alicante, Spain – Corneal, Cataract and Refractive Surgery Fellowship
- 2010–2017: Denizli Servergazi State Hospital – Ophthalmology Specialist
- 2004–2010: Pamukkale University Faculty of Medicine – Ophthalmology Specialization Training
- Akyol T, Parca O, Un ES, Toprak I, Pekel G (2026). Beyond the Cornea: Early Changes in Scleral, Iris, and Corneal Parameters After Corneal Collagen Cross-Linking. Journal of Clinical Medicine, 15(12): 4428.
- Toprak I, Gunes CE, Martin-Seker C, Parca O (2025). A novel metric to monitor early progression in keratoconus: epithelial backscatter. International Ophthalmology, 45(1): 253.
- Kanclerz P, Przewlocka K, Toprak I, Alio J (2023). The prevalence of keratoconus in northern Poland: A cross-sectional study of patients from a primary healthcare practice. Contact Lens & Anterior Eye, 46(4): 101846.
- Toprak I, Cavas F, Velázquez JS, Alio Del Barrio JL, Alio JL (2023). A three-dimensional morpho-volumetric similarity study of Down syndrome keratopathy vs. keratoconus. Eye and Vision, 10(1): 4.
- Toprak I (2023). To what extent is pregnancy-induced keratoconus progression reversible? A case report and literature review. European Journal of Ophthalmology, 33(1): NP37-NP41.
- Toprak I, Kilic D (2022). Current clinical approach to pediatric keratoconus patients. Expert Review of Ophthalmology, 17(2): 105-114.
- Toprak I, Cetin EN, Akbulut S, Pekel G, Yuksel S, Cobankara V (2022). Enhanced ectasia screening in patients with uveitis and isolated systemic inflammatory disease. Ocular Immunology and Inflammation, 30(2): 324-329.
- Toprak I, Gunes CE (2021). Increased epithelial backscatter: A novel finding in subclinical and clinical keratoconus. Clinical & Experimental Ophthalmology, 49(9): 1000-1008.
- Toprak I, Cavas F, Velázquez JS, Alio Del Barrio JL, Alio JL (2021). Three-dimensional morphogeometric and volumetric characterization of cornea in pediatric patients with early keratoconus. American Journal of Ophthalmology, 222: 102-111.
- Toprak I, Cavas F, Vega A, Velázquez JS, Alio Del Barrio JL, Alio JL (2021). Evidence of a Down Syndrome Keratopathy: A Three-dimensional (3-D) Morphogeometric and Volumetric Analysis. Journal of Personalized Medicine, 11(2): 82.
- Toprak I, Vega A, Espla E, Alio Del Barrio JL, Cavas F, Alio JL (2021). Diagnostic value of corneal epithelial and stromal thickness distribution profiles in forme fruste keratoconus and subclinical keratoconus. Cornea, 40(1): 61-72.
- Toprak I, Cavas F, Velázquez JS, Alio Del Barrio JL, Alio JL (2020). Subclinical keratoconus detection with three-dimensional (3-D) morphogeometric and volumetric analysis. Acta Ophthalmologica, 98(8): e933-e942.
- Toprak I (2020). Accelerated contact lens-assisted corneal collagen crosslinking and piggyback modification in a pediatric case with advanced keratoconus and thin cornea. Journal of Cataract & Refractive Surgery, 46(12): e35-e39.
- Alió JL, Toprak I, Rodriguez A (2019). Treatment of severe keratoconus hydrops with intracameral platelet-rich plasma injection. Cornea, 38(12): 1595-1598.
- Toprak I, Yaylali V, Yildirim C (2017). Visual, topographic and pachymetric effects of pediatric corneal collagen cross-linking. Journal of Pediatric Ophthalmology & Strabismus, 54(2): 84-89.
- Toprak I, Yaylali V, Yildirim C (2015). A combination of topographic and pachymetric parameters in keratoconus diagnosis. Contact Lens & Anterior Eye, 38(5): 357-362.
- Toprak I, Yaylali V, Yildirim C (2014). Factors affecting outcomes of corneal collagen crosslinking treatment. Eye (London), 28: 41-46.
- Toprak I, Kucukatay V, Yildirim C, Kilic-Toprak E, Kilic-Erkek O (2014). Increased systemic oxidative stress in patients with keratoconus. Eye (London), 28(3): 285-289.
- Toprak I, Yildirim C (2013). Scheimpflug parameters after corneal collagen crosslinking for keratoconus. European Journal of Ophthalmology, 23(6): 793-798.
- Toprak I, Yildirim C (2013). Effects of corneal collagen crosslinking on corneal topographic indices in patients with keratoconus. Eye & Contact Lens, 39(6): 385-387.
- Toprak I (2026). Predicting Early Keratoconus Progression Using Biomechanics via Multi-Machine Learning: A Multicenter 2-Year Prospective Cohort Study: Comment. Clinical & Experimental Ophthalmology, doi:10.1111/ceo.70157.
- Toprak I, Parca O (2025). Comment on: Epithelial Mapping Efficacy for Subclinical Keratoconus Identification. American Journal of Ophthalmology, 276: 406-407.
- Toprak I (2022). Comment on: Determining the Utility of Epithelial Thickness Mapping in Refractive Surgery Evaluations. American Journal of Ophthalmology, 241: 286-287.
- Toprak I (2021). Comment on: Repeatability of the Pentacam HR in Various Grades of Keratoconus. American Journal of Ophthalmology, 225: 206.
- Toprak I, Yaylali V (2019). Re: Hwang et al.: Distinguishing Highly Asymmetric Keratoconus Eyes Using Combined Scheimpflug and Spectral-Domain OCT Analysis. Ophthalmology, 126(7): e57-e58.
- Toprak I, Yaylali V, Yildirim C (2014). Response to Vinciguerra et al. Eye (London), 28: 1033-1034.
Other Areas
- Akkaya HS, Kilic-Toprak E, Cort A, Parca O, Toprak I (2026). Regenerative effects of RKI-1447 on human corneal endothelial cells: a comparative study. BMC Ophthalmology, 26(1): 504.
- Kilic-Toprak E, Cort-Donmez A, Toprak I (2024). Effects of Autologous Serum and Platelet-Rich Plasma on Human Corneal Endothelial Cell Regeneration: A Comparative Study. Eye & Contact Lens, 50(2): 106-111.
- Toprak I, Cetin EN, Gunes CE, Martin-Seker C (2021). Severe intraocular inflammation following hydrophilic acrylic phakic intraocular lens implantation in a case with concealed history of COVID-19: A case report and literature review. Ocular Immunology and Inflammation, 29(4): 662-665.
- Fariselli C, Toprak I, Al-Shymali O, Alio Del Barrio JL, Alio JL (2020). Corneal transplantation outcomes after the extrusion of an intrastromal keratoprosthesis: a pilot study. Eye and Vision, 7: 26.
- Toprak I, Fenkci SM, Fidan Yaylali G, Martin C, Yaylali V (2020). Early retinal neurodegeneration in preclinical diabetic retinopathy: a multifactorial investigation. Eye (London), 34(6): 1100-1107.
- Toprak I, Fenkci SM, Fidan Yaylali G, Martin C, Yaylali V (2020). Effect of microalbuminuria on corneal endothelium in patients with diabetes without retinopathy. Clinical and Experimental Optometry, 103(5): 625-629.
- Kilic-Toprak E, Toprak I, Caliskan S, Ozdemir Y, Demirtas O, Altintas F, Kucukatay V (2019). Oxidative Stress and Genotoxicity in Pterygium: A Systemic Investigation. Eye & Contact Lens, 45(6): 399-404.
- Toprak I, Yaylali V (2019). "Crack, Reduce, and Implant": A Safe Phaco Technique in a Case with Hard Brown Cataract. Case Reports in Medicine, 2019: 9043417.
- Toprak I, Yaylali V, Yildirim C (2017). Diagnostic consistency and relation between optical coherence tomography and standard automated perimetry in primary open angle glaucoma. Seminars in Ophthalmology, 32(2): 185-190.
- Toprak I, Yaylali V, Yildirim C (2017). Early deterioration in ellipsoid zone in eyes with non-neovascular age-related macular degeneration. International Ophthalmology, 37(4): 801-806.
- Toprak I, Yaylali V, Yildirim C (2016). Age-based analysis of choroidal thickness and choroidal vessel diameter in primary open-angle glaucoma. International Ophthalmology, 36(2): 171-177.
- Kilic-Toprak E, Toprak I, Kilic-Erkek O, Kucukatay V, Bor-Kucukatay M (2016). Increased erythrocyte aggregation in patients with primary open angle glaucoma. Clinical and Experimental Optometry, 99(6): 544-549.
- Toprak I, Yildirim C, Yaylali V (2015). Impaired photoreceptor inner segment ellipsoid layer reflectivity in mild diabetic retinopathy. Canadian Journal of Ophthalmology, 50(6): 438-441.
- Demir C, Toprak I, Gungen S, Arslan A (2015). Lacrimal gland fistula following severe head trauma. Case Reports in Medicine, 2015: 1-2.
- Yaylali V, Toprak I (2015). Exudative retinal detachment associated with complicated retrobulbar anesthesia. Open Journal of Ophthalmology, 5: 6-9.
- Toprak I, Yaylali V, Yildirim C (2014). Decreased photoreceptor inner segment/outer segment junction reflectivity in patients with idiopathic epimacular membrane. Eye (London), 28: 1126-1130.
- Toprak I, Yaylali V (2014). Bilateral cataract formation 25 years after indirect lightning injury. JCRS Online Case Reports, 2(1): e16-e17.
- Toprak I, Yildirim C, Yaylali V (2012). Optic disc topographic analysis in diabetic patients. International Ophthalmology, 32: 559-564.
- Toprak I, Kilic-Toprak E (2026). Letter Regarding: ESCALÓN: A Prospective Randomized Trial of Corneal Endothelial Cell Therapy in Subjects With Corneal Edema. Cornea, 45(9): e39-e40.
- Toprak I (2020). Re: Patel et al.: Predicting the Prognosis of Fuchs Endothelial Corneal Dystrophy by Using Scheimpflug Tomography. Ophthalmology, 127(10): e88-e89.
- Toprak I, Kilic D (2019). Using preoperative anterior segment optical coherence tomography to highly predict posterior capsule dehiscence in posterior polar cataract with simple image adjustments. Journal of Cataract & Refractive Surgery, 45(5): 704-705.
- Turkish Ophthalmology Association Cornea and Ocular Surface Unit
- Turkish Ophthalmology Association Cataract and Refractive Surgery Unit
- European Vision and Eye Research (EVER)
- Royal College of Surgeons of Edinburgh (MRCSEd)
- BMC Ophthalmology – Editorial Board Member (2020–2026)
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