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Liv Hospital Ulus

Thoracic Surgery

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Areas of Interests

Diagnosis and Surgical Treatment of Lung Cancer
Minimal Invasive Surgical Techniques (Video-Assisted Thoracoscopic Surgery, Robotic Surgery)
Treatment of Chest Wall Deformities (Pectus Surgery)
Mediastinal Surgery (Thymus Disorders, Surgery for Mediastinal Masses)
Mesothelioma Surgery
Cystic Lung Diseases
Diaphragm Pacing (Diaphragm Pacemaker Implantation)
Diagnosis and Surgical Treatment of Esophageal Diseases (Esophageal Cancer)
Endobronchial Treatment (Bronchoscopic Procedures, Stent Placement, Cryotherapy)
Digital Navigation Systems

Education:

1992 – 1998 Istanbul University, Cerrahpaşa Faculty of Medicine (English Program)
1999 – 2006 Marmara University, Residency in Thoracic Surgery
2012 – 2013 Harvard University, Brigham and Women’s Hospital (Boston), Fellowship in Thoracic Surgery

Academic Experience:

2011 – 2013 Chief Resident – Süreyyapaşa Chest Diseases and Thoracic Surgery Training and Research Hospital
2013 – 2018 Assistant Professor – Marmara University, Faculty of Medicine
2018 – 2026 Associate Professor – Marmara University, Faculty of Medicine
2026 – October: Professor – Marmara University, Faculty of Medicine

Professional Experience:

2026 – Present: Thoracic Surgeon (Professor) – Liv Hospital Ulus
2026 – October 2026: Thoracic Surgeon (Professor) – Marmara University
2018 – 2026: Thoracic Surgeon (Associate Professor) – Marmara University
2013 – 2018: Thoracic Surgeon (Assistant Professor) – Marmara University
2012 – 2013: Fellow in Thoracic Surgery – Harvard University, Brigham and Women’s Hospital

Articles Published in International Primary Indices:

Yıldızeli B, Lacin T, Batırel HF, Yüksel M (2004). Complications and management of long-term central venous access catheters and ports. J Vasc Access, 5(4), 174-178.
Eti Z, Lacin T, Yıldızeli B, Dogan V, Gogus FY, Yuksel M (2005). An uncommon complication of thoracic epidural anesthesia: pleural puncture. Anesth Analg., 100(5), 1540-1541.
Yıldızeli B, Lacin T, Baltacıoglu F, Batırel HF, Yüksel M (2005). Approach to fragmented central venous catheters. Vascular, 13(2), 120-123.
Yuksel M, Ozyurtkan MO, Lacin T, Yildizeli B, Batirel HF (2006). The role of fluoroscopy in the removal of tracheobronchial pin aspiration. Int J Clin Pract., 60(11), 1451-1453.
Lacin T, Batırel HF, Ozer K, Demirutku A, Ahıskalı R, Yuksel M (2007). Safety of a thermal vessel sealer on main pulmonary vessels. Eur J Cardiothorac Surg., 31(3), 482-485.
Batirel HF, Metintas M, Caglar HB, Yildizeli B, Lacin T, Bostanci K, Akgul AG, Evman S, Yuksel M (2008). Trimodality treatment of malignant pleural mesothelioma. J Thorac Oncol., 3(5), 499-504.
Bezer M, Aydin N, Erol B, Laçin T, Güven O (2009). Unusual migration of K-wire following fixation of clavicle fracture: a case report. Ulus Travma Acil Cerrahi Derg., 15(3), 298-300.
Alpay L, Lacin T, Mısırlıoglu AK, Yalçınkaya I (2011). Tumor recurrence in an open window thoracotomy space. Eur J Cardiothorac Surg., 40(2), 527.
Alpay L, Lacin T, Atinkaya C, Kiral H, Demir M, Baysungur V, Okur E, Yalcinkaya I (2012). Videoassisted thoracoscopic removal of pulmonary hydatid cysts. Eur J Cardiothorac Surg., 42(6), 971-975.
Okur HK, Yuksel M, Lacin T, Baysungur V, Okur E (2013). Detection of reactive oxygen metabolites in malignant and adjacent normal tissues of patients with lung cancer. World J Surg Oncol., 11(9), 1-5.
Alpay L, Laçin T, Kanbur S, Kıral H, Ersöz E, Bayram S, Dogruyol T, Baysungur V, Yalçınkaya I (2013). Are the F-18-FDG positron emission tomography/computed tomography findings in bronchopulmonary carcinoid tumors different than expected? Hellenic J Nuclear Med, 16(3), 213-217.
Alpay L, Laçin T, Koşar A, Mısırlıoglu A, Öztas S, Sönmez H, Coskun T, Baysungur V, Yalçınkaya I (2014). Diagnostic Algorithm in Patients with Superior Vena Cava Syndrome and Efficacy of Cervical Mediastinoscopy. ACTA Chirurgica Belgica, 1145, 309-312.
Alpay L, Laçin T, Teker D, Okur E, Baysungur V, Kanbur S, Mısırlıoglu AK, Sonmez H, Yalçınkaya I, Kıyak M (2014). A comparative cost analysis study of lobectomy performed via video-assisted thoracic surgery versus thoracotomy in Turkey. Videosurgery and Other Miniinvasive Techniques, 3, 409-414.
Alpay L, Lacin T, Kanbur S, Dogruyol T, Baysungur V, Yalcinkaya I (2014). Congenital broncho-esophageal fistulas in adult patients. The Turkish Journal of Gastroenterology, 25(5), 578-79.
Alpay L, Evman S, Dogruyol T, Kıral H, Laçin T, Vayvada M, Baysungur V, Yalçınkaya I (2015). Survival in adenosquamous cancer of the lung: is it really so unfavorable? Turkish Journal of Thoracic and Cardiovascular Surgery, 23(4), 690-694.
Kıral H, Evman S, Tezel Ç, Alpay L, Laçin T, Baysungur V, Yalçınkaya I (2015). Pulmonary Resection in the Treatment of Life-Threatening Hemoptysis. Annals of Thoracic and Cardiovascular Surgery, 21(2), 125-131.
Alpay L, Laçin T, Dogruyol T, Baysungur V, Yalçınkaya I (2015). A thoracic and cardiovascular surgeon in Sureyyapasa Hospital: Siyami Ersek. Turkish Journal of Thoracic and Cardiovascular Surgery, 23(1), 199-203.
Alpay L, Laçin T, Ocakçıoglu I, Evman S, Dogruyol T, Vayvada M, Baysungur V, Yalcinkaya I (2015). Is Video-Assisted Thoracoscopic Surgery Adequate in Treatment of Pulmonary Hydatidosis? The Annals of Thoracic Surgery,100(1), 258-262.
Bilgi Z, Ermerak NO, Laçin T, Bostancı K, Yüksel M (2016). Previously complicated Nuss procedure does not preclude blind removal of the bar. Thorac Cardiovasc Surg, 64, 83-86.
Lacin T, Yıldızeli B, Eryüksel E, Ceyhan B, Karakurt S, Bekiroğlu N, Çelikel T, Yüksel M (2017). Whole lung lavage for pulmonary alveolar proteinosis: still the most up-to-date treatment. Turkish Journal of Thoracic and Cardiovascular Surgery, 25(1),110-116.
Bilgi Z, Ermerak NO, Çetinkaya Ç, Laçin T, Yüksel M (2017). Risk of serious perioperative complications with removal of double bars following the Nuss procedure. Interactive Cardiovascular and Thoracic Surgery, 24, 257-259.
Yuksel M, Lacin T, Ermerak NO, Sirzai EY, Sayan B (2018). Minimally invasive repair of pectus carinatum. Ann Thorac Surg Mar;105(3):915-923.
Topaloğlu N, Olgun Yıldızeli Ş, Şener G, Laçin T, Şehirli Ö, Bozkurtlar E, Çelikel Ç, Ceyhan B (2018). Protective effect of cysteinyl leukotriene receptor antagonist montelukast in bleomycin-induced pulmonary fibrosis. Turkish Journal of Thoracic and Cardiovascular Surgery, 26(4):588-597.
Batirel HF, Metintas M, Caglar HB, Ak G, Yumuk PF, Ahiskali R, Bozkurtlar E, Bekiroglu N, Lacin T, Yildizeli B, Yuksel M. Macroscopic complete resection is not associated with improved survival in patients with malignant pleural mesothelioma. J Thorac Cardiovasc Surg, 155(6),2724-2733.
Bostanci K, Ozyurtkan MO, Polat MO, Batirel H, Lacin T, Yuksel M, Stamenovic D (2020). Variations in pulmonary fissural anatomy: a medicolegal autopsy study of 256 cases. ANZ J Surg, 90(4),608-611.
Cevik M, Dartan G, Ulker M, Bezci K, Deliorman G, Cagatay P, Lacin T, Cinel IH, Aksu B, Keskin Y, Can ZS, Yurdun T, Susleyici B (2020). Evaluation of cytotoxicity and mutagenicity of waste water form Istanbul: Data from hospitals and advanced wastewater treatment plant. Bull Environ Contam Toxicol, 104(6),852-857.
Ercelep O, Alan O, Telli TA, Tuylu TB, Arıkan R, Demircan NC, Simsek ET, Babacan NA, Kaya S, Dane F, Bozkurtlar E, Ones T, Lacin T, Yumuk PF (2021). Differences in PET/CT standardized uptake values involvement and survival compared to histologic subtypes of lung adenocarcinoma. Tumori, 107(3),231-237. doi: 10.1177/0300891620950475.
COVIDSurg Collaborative, GlobalSurg Collaborative (2021). SARS-CoV-2 vaccination modelling for safe surgery to save lives: data from an international prospective cohort study. Br J Surg, Mar 24:znab101. doi: 10.1093/bjs/znab101. Online ahead of print.
COVIDSurg Collaborative; GlobalSurg Collaborative (2021). Timing of surgery following SARS-CoV-2 infection: an international prospective cohort study. Anaesthesia, 76(6),748-758.
COVIDSurg Collaborative; GlobalSurg Collaborative. (2021) Effects of pre-operative isolation on postoperative pulmonary complications after elective surgery: an international prospective cohort study. Anaesthesia. 2021 Nov;76(11):1454-1464. doi: 10.1111/anae.15560.
COVIDSurg Collaborative; GlobalSurg Collaborative. (2022) SARS-CoV-2 infection and venous thromboembolism after surgery: an international prospective cohort study. Anaesthesia. 2022 Jan;77(1):28-39. doi:10.1111/anae.15563.
Ak N, Ozkan B, Yenigun MB, Yilmazbayhan D, Toker A, Ferhatoglu F, Yasar A, Dizbay Sak S, Tanju S, Dilege S, Erus S, Bulutay P, Firat P, Molinas Mandel N, Kilickap S, Onder S, Dikmen E, Alan O, Yumuk PF, Bozkurtlar E, Lacin T, Yildizeli B, Ozturk A, Kocaturk C, Karapinar K, Urer N, Oyan B, Aydiner A, Demirkazik A, Eralp Y. (2021) The role of adjuvant chemotherapy in resected stage I non - small cell lung cancer: A Turkish Oncology Group Study. J BUON. 2021 May-Jun;26(3):819-829.
Ermerak NO, Uprak KT, Emran M, Lacin T, Yildizeli B, Yegen C. (2024) Esophageal Perforation During Intragastric Balloon Therapy: Management of a Patient with Late Referral. Obes Surg. 2024 Jan;34(1):272-273. doi: 10.1007/s11695-023-06929-0.
Dempsey PW, Sandu CM, Gonzalezirias R, Hantula S, Covarrubias-Zambrano O, Bossmann SH, Nagji AS, Veeramachaneni NK, Ermerak NO, Kocakaya D, Lacin T, Yildizeli B, Lilley P, Wen SWC, Nederby L, Hansen TF, Hilberg O. (2024). Description of an activity-based enzyme biosensor for lung cancer detection. Commun Med 2024 Mar 5;4(1):37. doi: 10.1038/s43856-024-00461-7.
Lacin T, Ermerak NO, Onen HU, Aridas AG. (2025). Surgical Repair of Pectus Arcuatum.Thorac Cardiovasc Surg. 2025 Jul 7. doi: 10.1055/a-2642-1738. Online ahead of print.
NIHR Global Health Research Unit on Global Surgery. (2026). 30-day postoperative mortality and the effects of hospital preparedness during the COVID-19 pandemic: a pooled analysis of prospective international cohort studies. Lancet Reg Health Eur. 2026 Jan 29;62:101566. doi: 10.1016/j.lanepe.2025.101566. eCollection 2026 Mar.
Yardımcı EH, Arıdas AG, Aslan S, Lacin T, Bostancı K (2026). Rethinking pN1 Disease in Non-Small Cell Lung Cancer: Anatomical Subclassification, Surgical Extent, and Survival Outcomes. J Clin Med 2026 May 20;15(10):3950. Doi: 10.3390/jcm15103950.

Items Published in the Secondary Index:

Yüksel M, Özyurtkan MO, Topaloğlu N, Laçin T (2005). Pulmonary arterivenous malformation treated by lobectomy. Marmara Medical Journal, 18(2), 87-89.
Ones T, Dede F, Lacin T, Calıskan B, Inanır S, Erdil T, Turoglu H (2008). Autolobectomy in Swyer-James (Mcleod’s) Syndrome: value of preoperative V/Q scan. The Internet Journal of Nuclear Medicine, 5(1).
Yalcinkaya I, Evman S, Lacin T, Alpay L, Kupeli M, Ocakcioglu I (2017). Video-assisted minimally invasive diaphragmatic plication: feasibility of a recognised procedure through an uncharacteristichybrid approach. Surg Endosc, 13,1772-1777.
Bektaşoğlu KP, Ermerak NO, Cimşit C, Çetinkaya Ç, Özbakır H, Bekiroğlu N, Laçin T, Yüksel M (2017). Evaluation of the internal thoracic artery blood flow before and after Nuss operation: is it reversible? Marmara Medical Journal, 30.24-29.
Bilgi Z, Batırel HF, Yıldızeli B, Bostancı K, Laçin T, Yüksel M (2017). No adverse outcomes of video-assisted thoracoscopic surgery resection of cT2 Non-small cell lung cancer during the learning curve period. Korean J Thorac Cardiovasc Surg 50.275-280.
Mirzayev A, Cakmak G, Abdullayev R, Lacin T, Aykac Z, Saracoglu A (2024). Oxygen titration with Oxygen Reserve Index in minimally invasive repair of pectus excavatum, a randomized controlled trial. North Clin Istanb. 2024 Sep 11;11(5):382-390. doi: 10.14744/nci.2023.45556. eCollection 2024.PMID: 39431038

Review Article Published in a Primary Index:

Lacin T, Swanson S (2013). Current costs of video-assisted thoracic surgery (VATS) lobectomy. J Thorac Dis, 5(3),190-193.

Articles Published in National Journals (in English):

Bostancı K, Özyurtkan MO, Lacin T, Polat O, Yüksel M (2006). Analysis of thoracic pathologies and anomalies in the Turkish population. Turkish Respiratory Journal, 7(1), 22-24.
Batırel HF, Laçin T, Yıldızeli B, Bostancı K, Yüksel M (2006). Results of surgery in asymptomatic lung lesions with special emphasis on lung cancers. Turkish Respiratory Journal, 7(3), 109-112.
Batırel HF, Gemici C, Yıldızeli B, Laçin T, Akgül AG, Evman S, Çağlar HB, İlhan M, Yüksel M (2008). Results of transthoracic esophagectomy following chemoradiation in locally advanced esophageal cancer. Turkish Journal of Cancer, 38(1), 20-25.
Duman D, Kuyucu T, Koç EN, Laçin T, Aksoy F (2014). Plevranın Mezotel Kisti. Türkiye Klinikleri Journal of Case Reports, 22(3), 197-199.

Articles Published in National Journals:

Laçin T, TOPÇU S (2015). Surgical Procedures Performed in Management of Malignant Pleural Effusions. Eurasian Journal of Pulmonology, 17(1), 10-14.
Laçin T., Yıldızeli B., Ahıskalı R., Turoğlu T., Yüksel M (2001). Mediastinal paratiroid lipoadenom; olgu sunumu. Heybeliada Tıp Bülteni, 7(2), 46-48.
Özyurtkan O., Laçin T., Yıldızeli B., Kaya H., Kuyucu T., Yüksel M (2001). Mediastinal liposarkom. Heybeliada Tıp Bülteni, 7(3), 62-64.
Laçin T, Evman S, Kodallı N, Yıldızeli B, Yüksel M (2004). Özofagus kanserine bağlı trakeal darlığın trakeobronşiyal Y stent ile açılması: olgu sunumu. Heybeliada Tıp Bülteni, 10(1,2,3), 87-90.
Laçin T, Yıldızeli B, Yüksel M (2004). Çocuklarda trakeobronşiyal yabancı cisim aspirasyonu. Çocuk Forumu, 11-14.
Yüksel M, Batırel HF, Laçin T (2004). Morgagni Diyafragm hernisinde laparoskopik yaklaşım. Endoskopik Laparoskopik ve Minimal İnvaziv Cerrahi Dergisi, 11(4), 169-173.
Laçin T, Kodallı N, Yıldızeli B, Yüksel M (2005). Tipik ve atipik pulmoner karsinoid tümörler. Heybeliada Tıp Bülteni, 11(1), 31-35.
Akgül AG, Laçin T, Batırel HF, Kodallı N, Yüksel M (2005). Benign ve malign trakeobronşiyal darlık nedeniyle santral havayolu obstrüksiyonu gelişen hastalarda stent yerleştirilmesi. Heybeliada Tıp Bülteni, 11(1), 44-49.
Özyurtkan MO, Bostancı K, Laçin T, Akgül AG, Yüksel M (2005). Juguler venöz kateterizasyon sonrası görülen bir pnömotoraks olgusu. Heybeliada Tıp Bülteni, 11(3), 140-142.
Sönmez H, Alpay L, Laçin T, Mısırlıoğlu A, Baysungur V, Kapıcıbaşı O, Okur E, Yalçınkaya I (2013). Sol akciğer üst lob veya santral yerleşimli küçük hücreli dışı akciğer kanserlerinde extended servikal mediastinoskopinin yeri. Türkiye Klinikleri Akciğer Arşivi, 14(2), 55-60.
Alpay L, Ocakçıoglu I, Dogruyol T, Laçin T, Baysungur V, Yalçınkaya I (2013). Diaphragma injury following blunt trauma. The Journal of Kartal Training and Research Hospital, 24(2), 110-113.

International Book Chapter:

Advanced Thoracic Surgery (Editors: Akın Eraslan Balcı, Hasan Ersöz, Mustafa Yüksel) Bölüm 40, Tunç Laçin. Effect of diaphrgm pacing on quality of life: The state of art (s:431-437), Akademisyen Bookstore, İstanbul, 2021, ISBN: 978-625-7679-74-9.

National Book Section:

Göğüs Cerrahisi (Editörler: Mustafa Yüksel, N. Göksel Kalaycı). Bölüm 18, Laçin T, Yüksel M. Bronşiyal Gland Tümörleri (s: 263-271), Bilmedya Grup, İstanbul, 2001, ISBN: 975-97715-0-0.
Toraks Travmaları (Editörler: Mustafa Yüksel, Güven Çetin). Bölüm 1, Laçin T, Yüksel M. Travmalı Hastaya Yaklaşım (s: 1-14), Turgut Basımevi, İstanbul, 2003, ISBN: 975-7958-66-2.
Çağdaş Videotorakoskopik Cerrahide Teknikler ve Sonuçlar, Bölüm adı: Plevral Biyopsi (2014)., Laçin T, Nobel Tıp Kitabevleri, Editör: Toker Alper, Batırel Hasan, ISBN:978-605-335-076-7.
Çağdaş Videotorakoskopik Cerrahide Teknikler ve Sonuçlar, Bölüm adı: Segmentektomiler (2014)., Swanson S, Laçin T, Nobel Tıp Kitabevleri, Editör: Toker Alper, Batırel Hasan, ISBN:978-605-335-076-7.
Çağdaş Videotorakoskopik Cerrahide Teknikler ve Sonuçlar, Bölüm adı: Sag Üst Lobektomi (2014)., Swanson S, Laçin T, Nobel Tıp Kitabevleri, Editör: Toker Alper, Batırel Hasan, ISBN:978-605-335-076-7.
Çağdaş Videotorakoskopik Cerrahide Teknikler ve Sonuçlar, Bölüm adı: Sol Üst Lobektomi (2014)., Swanson S, Laçin T, Nobel Tıp Kitabevleri, Editör: Toker Alper, Batırel Hasan, ISBN:978-605-335-076-7.
Gögüs Cerrahisi "Kırmızı Kitap", Bölüm adı: Entübasyon Hasarı (2015) Laçin T, Nobel Tıp, Editör: Yüksel Mustafa, Balcı Akın Eraslan, Basım sayısı:2, Sayfa Sayısı 1139, ISBN:978-605-335-122-1.
Gögüs Cerrahisi "Kırmızı Kitap", Bölüm adı: Gastroözofageal reflü hastalıgı ve cerrahisi (2015) Laçin T, Nobel Tıp, Editör: Yüksel Mustafa, Balcı Akın Eraslan, Basım sayısı:2, Sayfa Sayısı 1139, ISBN:978-605-335-122-1.
Gögüs Cerrahisi "Kırmızı Kitap", Bölüm adı: Reflü Cerrahisinin Komplikasyonları (2015) Laçin T, Nobel Tıp, Editör:Yüksel Mustafa, Balcı Akın Eraslan, Basım sayısı:2, Sayfa Sayısı 1139, ISBN:978-605-335-122-1
Alpay L, Laçin T, Ocakçıoğlu İ, Yalçınkaya İ. Minimal İnvaziv Cerrahi Yaklaşım. In Akciğer Hidatik Kisti. Editör:Doç Dr. İrfan Yalçınkaya, TÜSAD Eğitim Kitapları Serisi, Ekim 2016, 89-95.

Turkish Thoracic Surgery Association
European Association for Cardiothoracic Surgery (EACTS) (Thoracic Domain Member (2015-2018)
European Society of Thoracic Surgeons (ESTS)
European Respiratory Society (ERS)
Society of Thoracic Surgeons (STS)
Chest Wall International Group (CWIG) (Executive Board Member 2023- present)
Pectus Association Istanbul
Turkish Thoracic Association
Istanbul Medical Chamber

ESTS-DUTCH Society for Lung Surgery Annual Meeting Travel Grant 2011, Alpay L, Lacin T, Okur E, Baysungur V, Mısırlıoglu A, Demir M, Sonmez H, Yalcınkaya I, Teker D, Kıyak M. Research titled 'A comparative cost analysis study of lobectomy performed via video-assisted thoracic surgery and thoracotomy', European Society of Thoracic Surgeons (ESTS), 19th European Conference on General Thoracic Surgery, Marseille-France, 5-8 June 2011 (poster).
Royal Academy of Engineering, Leaders in Innovations Fellowships. First Place. February 2018
Turkish Thoracic Society International Manuscript First place, 2019. Batırel HF, Metintas M, Caglar HB, Ak G, Yumuk PF, Ahiskali R, Bozkurtlar E, Bekiroglu N, Lacin T, Yildizeli B, Yuksel M (2018). Macroscopic complete resection is not associated with improved survival in patients with malignant pleural mesothelioma. J Thorac Cardiovasc Surg, 155(6):2724-2733.
Lacin T, Pashayev J, Ermerak NO, Tok RN, Demircioglu O. A new criteria proposal for determining the number of the bars to be placed in a patient with pectus excavtum. 24th Annual Congress of the Chest Wall International Group (CWIG), 23-25 October 2024, Phoenix, Arizona.