Prof. MD.

Merdan Fayda

Radiation Oncology

Interests

  • Three Dimensional Brachytherapy
  • Four Dimensional (4D) Radiotherapy
  • Stereotactic RT & IMRT
  • Breast Cancer, Gynecological Cancers
  • Head – Neck Cancers
  • Urological Tumors, Gastrointestinal Cancers
  • Lung Cancer
  • Central Nervous System Tumors & Metastases
  • Skin Cancers
  • Soft Tissue Tumors

11
h-index
49
uluslararası makale
Education: 
  • Istinye University Medical Faculty, Professor Doctor (2017 – Continued)
  • Istine University Medical Faculty Associate Professor Doctor (2016 – 2017)
  • Liv Hospital Radiation Medicine Center, Tbilisi, Georgia, Radiation Oncology Consulting Docor (2016 – 2019)
  • Liv Hospital, Radiation Oncology (2015 – Continued)
  • Istanbul University Oncology Institution, Associate Professor (2012 – 2015)
  • Stereotactic Radiotherapy, Thoracic Oncology, University of North Carolina, NC, USA (2010 – 2011)
  • Kocaeli University Radiation Oncology Department, Associate Professor Assistant (2006 – 2009)
  • GATA Radiation Oncology Department, Specialist Doctor, Reserve Officer (2004 – 2005)
  • Istanbul University, Medical Faculty, Dr.R.A. (1999 – 2004)
  • Istanbul University, Medical Faculty, Under-Graduate (1993 – 1999)

Experience:
  • Istinye University Medical Faculty
  • Liv Hospital Ulus
  • Istanbul University Oncology Institution
  • University of North Carolina, NC, USA
  • Kocaeli University Medical Faculty
  • Istanbul University, Medical Faculty
Research: Count
  • Tambas M, Tavli B, Bilici N, Dizman A, Sertel H, Fayda M. Computed Tomography-Guided Optimization of Needle Insertion for Combined Intracavitary/Interstitial Brachytherapy With Utrecht Applicator in Locally Advanced Cervical Cancer. Pract Radiat Oncol. 2021 Feb 5:S1879-8500(21)00043-6. doi: 10.1016/j.prro.2021.01.008. Epub ahead of print. PMID: 33556579.
  • Tambaş M, Fayda M. Central Nervous System Cancer in Elderly. Saka B, editor. Geriatric Oncology. Ankara: Turkey Clinic; 2018. p. 28-35
  • Fayda M, Isin M, Tambas M, Guveli M, Meral R, Altun M, Sahin D, Ozkan G, Sanli Y, Isin H, Ozgur E, Gezer U. Do Circulating Long Non-Coding RNAs (lncRNAs) (LincRNA-p21, GAS 5, HOTAIR) Predict the Treatment Response in Patients with Head and Neck Cancer Treated with Chemoradiotherapy? Tumor Biology, 2015, 19 October, DOI: 10.1007/s13277-015-4189-1.
  • Onder S, Fayda M, Karanlık H, Bayram A, Şen F, Cabioglu N, Tuzlalı S, İlhan R, Yavuz E. Loss of ARID1A expression is associated with poor prognosis in invasive micropapillary carcinomas of the breast: A clinicopathologic and immunohistochemical study with long-term survival analysis. Breast J. 2017 May 23. doi: 10.1111/tbj.12823. [E-pub ahead of print]
  • Fayda M, Gezer U. GAS5 oligonucleotides as therapeutic agents in breast cancer. Trans Cancer Res 2016. doi: 10.21037/tcr.2016.08.4
  • Fayda M, Tambaş, M, Karanlık H. Is sentinel lymph node biopsy enough for auxiliary macrometastasis? Turkish Journal of Surgery, 2015, Vol.31(4), pp.253-255.
Publications
  • Tambaş M, Fayda M. Central Nervous System Cancer in Elderly. Saka B, editor. Geriatric Oncology. Ankara: Turkey Clinic; 2018. p. 28-35
  • Fayda M, Isin M, Tambas M, Guveli M, Meral R, Altun M, Sahin D, Ozkan G, Sanli Y, Isin H, Ozgur E, Gezer U. Do Circulating Long Non-Coding RNAs (lncRNAs) (LincRNA-p21, GAS 5, HOTAIR) Predict the Treatment Response in Patients with Head and Neck Cancer Treated with Chemoradiotherapy? Tumor Biology, 2015, 19 October, DOI: 10.1007/s13277-015-4189-1.
  • Onder S, Fayda M, Karanlık H, Bayram A, Şen F, Cabioglu N, Tuzlalı S, İlhan R, Yavuz E. Loss of ARID1A expression is associated with poor prognosis in invasive micropapillary carcinomas of the breast: A clinicopathologic and immunohistochemical study with long-term survival analysis. Breast J. 2017 May 23. doi: 10.1111/tbj.12823. [Epub ahead of print]
  • Fayda M, Gezer U. GAS5 oligonucleotides as therapeutic agents in breast cancer. Transl Cancer Res 2016. doi: 10.21037/tcr.2016.08.4
  • Fayda M, Tambaş, M, Karanlık H. Is sentinel lymph node biopsy enough for auxiliary macrometastasis? Turkish Journal of Surgery, 2015, Vol 31(4), pp. 253-255.
  • Aydiner A, Sen F, Tambas M, Ciftci R, Eralp Y, Saip P, Karanlik H, Fayda M, Kucucuk S, Onder S, Yavuz E, Muslumanoglu M, Igci A. Metaplastic Breast Carcinoma Versus Triple-Negative Breast Cancer: Survival and Response to Treatment. Medicine (Baltimore), 2015 Dec;94(52):e2341.
  • Karanlık H, Özgür İ, Şahin D, Fayda M, Önder S, Yavuz E. Intraoperative ultrasound reduces the need for re-excision in breast conserving surgery, World Journal of Surgical Oncology, 2015 Nov 24;13(1):321.
  • Goldin G., Zagar T., Carter J., Fayda E.M., Prasad S., Fakiris S., Chen R., Morris D., Marks L., Schreiber E., Stereotactic Body Radiation Therapy For Early Stage Lung Cancer: Quantifying The Effect Of Tracking With Respiratory Motion On Chest Wall Dosimetry, American Society for Radiation Oncology 55th Annual Meeting, USA, 22-25 September 2013, vol.87, pp.733-734
  • Çakır A, Akgün Z, Fayda EM, Ağaoğlu F.  Comparison of three dimensional conformal radiation therapy, intensity modulated radiation therapy and volumetric modulated arc therapy for low radiation exposure of normal tissue in patients with prostate cancer. Asian Pacific Journal of Cancer Prevention, 2015, 16(8), 3365-3370.
  • Fried D., Miller S., Fayda E.M., Morris D., Zagar T., Lawrence M., Schreiber E., Ivanoviç M., Mccartney W., Marks L., "Estimating The Alpha/Beta Ratio For Radiation-Induced Ct Density Changes In Patients Receiving Thoracic Radiation: Comparison Of Data From Srs And Conventional Fractionation", 54th Annual Meeting of the American-Society-for-Radiation-Oncology (ASTRO), BOSTON, ABD, 28-31 Ekim 2012, pp.675-675
  • Goldin G., Zagar T., Fayda E.M., Marks L., Fried D., Miller S., Chen R., Schreiber Ec E., Egan T., Morris D., "Clinical Outcomes Of Cyberknife Radiosurgery For Early Stage Lung Cancer: Low Chest Wall Toxicity Rates Associated With Tracking", JOURNAL OF THORACIC ONCOLOGY, PHILADELPHIA, ABD, 15-15 Eylül 2012, pp.274-275
  • Fayda E.M., Riguera D., Yirmibeşoğlu E., Laxrence M., Rivera P., Xie L., Stefanescu M., Marks L., "The Lack Of Association Between Cardiopulmonary Dosimetric Parameters And Short-Term Changes In Quality Of Life Following Thoracic Irradiation", INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, NEW YORK, ABD, 1-1 Ocak 2011, pp.604-605
  • Özkurt E, Tükenmez M, Çelet B, Öner G, Güven E, Müslümanoğlu M, İğci A, Özmen V, Fayda M, Cabioğlu N. Radiotherapy Does Not Increase Implant/Expander Loss in Breast Cancer Patients Who Underwent Immediate Breast Reconstruction. Annals of Surgical Oncology, Supplement Volume 22(2);May, 2015
  • Karanlık H, Fayda M, İlker Ö, Kurul S.  COMPARISON OF IMPLANT-BASED IMMEDIATE BREAST RECONSTRUCTION WITH AND WITHOUT VICRYL MESH.  14. St. Gallen International Breast Cancer Conference, 2015.
  • Tükenmez M, Kulle CB, Velidedeoğlu M, Agcaoglu O, Parlakgul G, Aydogan F, Onder S, Bozdogan A, Ozkurt E, Muslumanoglu M, İgci A, Dinccag A, Özmen V, ÇELİK Varol, Karanlık H, Fayda EM, Şen F, Aydıner A, Cabioğlu N.  Clinical distuingishing characteristics and management of phyllodes tumors of the breast.  2015 ASCO Annual Meeting, 33(5), 12060
  • Çelet BÖ, Kozanoglu E, Soluk MT, Fayda M.  Early fat grafting following PMRT improves cosmetic outcome in two-stage breast reconstruction.  Barcelona Breast Meeting 11-13 Mart 2015
  • Fayda M. Is Sentinel Lymph Node Biopsy Enough for Axillary Macrometastasis? World Congress on Breast Cancer, Birmingham, UK, 2-4 August 2015
  • Fayda M.  Local-Regional Therapy Considerations in Patients Receiving Preoperative Chemotherapy.  SUNY - YÖK Joint International Public Health and Medical Sciences Conference, April 2015.
  • Karanlık H, Bayrak S, Fayda EM, Özgür İ, Kurul S.  Comparison of implant-based immediate breast reconstruction with and without vicryl mesh.  14 th St. Gallen International Breast Cancer ConferencePrimary Therapy of Early Breast Cancer, 2015, 24(1), 132-132.
  • Karanlık H, Saip P, Fayda M, Yavuz E, Eralp Y, Küçücük S, Kurul S, Aydıner A. Magnetic resonance imaging as a predictor of pathologic response rates in patients treated with neoadjuvant chemotherapy. 9th European Breast Cancer Conference (EBCC), 2014, 50(2), 154.
  • Altun M, Tambaş M, Fayda M (2014).  Nasopharyngeal carcinoma patients with new primaries.  ASCO Annual Meeting 2014, 32(5), 6087.
  • Karabulut S, Tas F, Tastekin D, Karabulut M, Yasasever CT, Çiftçi R, Güveli M, Fayda M, Vatansever S, Serilmez M, Disci R, Aydıner A. The diagnostic, predictive, and prognostic role of serum epithelial cell adhesion molecule (EpCAM) and vascular cell adhesion molecule-1 (VCAM-1) levels in breast cancer. Tumour Biology. 2014 Jun 3. [Epub ahead of print] PMID: 24891186.
  • Fayda M, Karanlik H. Axillary versus sentinel-lymph-node dissection for micrometastatic breast cancer. Lancet Oncol. 2013 Jun;14(7):e250. PMID: 23725703.
  • Fayda M, Kebudi R, Dizdar Y, Gorgun O, Gun F, Aksu G, Ayan I. Spontaneous pneumothorax in children with osteosarcoma: report of three cases and review of the literature. Acta Chir Belg. 2012 Sep-Oct;112(5):378-81. PMID: 23175928
  • Yirmibesoglu E, Higginson DS, Fayda M, Rivera MP, Halle J, Rosenman J, Xie L, Marks LB. Challenges scoring radiation pneumonitis in patients irradiated for lung cancer. Lung Cancer. 2012 Jun;76(3):350-3. PMID: 22230037
  • Fayda M, Chen R. Axillary vs sentinel lymph node dissection for invasive breast cancer. JAMA. 2011 Jun 8;305(22):2289; author reply 2290-1. PMID: 21642673
  • Fayda M, Aksu G, Agaoglu FY, Karadeniz A, Darendeliler E, Altun M, Hafiz G. The role of surgery and radiotherapy in treatment of soft tissue sarcomas of the head and neck region: review of 30 cases. J Craniomaxillofac Surg. 2009 Jan;37(1):42-8. Epub 2008 Sep 18. PubMed PMID: 18804382.
  • Inan N, Fayda M, G. Aksu, G. Akansel, B. Muezzinoglu ve A. Arslan. “Leiomyoma of the Seminal Vesicle Mimicking Tumoral Extension of Prostatic Carcinoma.” Acta Chir Belg, 109, 811-814 (2009). PubMed PMID: 20184078.
  • Dizdar Y, Küçücük S, Sağlam SK, Fayda M, Uzel O, Camlıca H. Clinical Efficacy of Transdermal Fentanyl in Adults with Cancer-Related Pain:An Open Multicentre Study. Turkiye Klinikleri J Med Sci 2009;29(4):821-5.
  • Iş G, Taş S, Corapcioğlu F, Fayda M. Is it destiny or just migration pathway theory? Familial germ cell tumor with the same histopathologic subtype in a father and son. Pediatr Neurosurg. 2009;45(2):160. Epub 2009 Mar 25. PubMed PMID:19321956.
  • Aksu G, Fayda M, Saynak M, Karadeniz A. Spinal cord compression due to vertebral hemangioma. Orthopedics. 2008 Feb;31(2):169. PubMed PMID: 19292199.
  • Uygun K, Bilici A, Karagol H, Caloglu M, Cicin I, Aksu G, Fayda M, Uzunoglu S. The comparison of weekly and three-weekly cisplatin chemotherapy concurrent with radiotherapy in patients with previously untreated inoperable non-metastatic squamous cell carcinoma of the head and neck. Cancer Chemother Pharmacol. 2009Aug;64(3):601-5. Epub 2009 Jan 3. PubMed PMID: 19123002.
  • Uygun K, Aksu G, Cicin I, Karagol H, Kocak Z, Fayda M, Binici A, Uzunoglu F. The efficiency of single agent docetaxel in patients with platinum-refractory non-small cell lung carcinoma. Med Oncol. 2008;25(4):408-14. Epub 2008 Mar 5. PubMed PMID: 18320363.
  • Yalug I, Corapcioglu F, Fayda M, Aksu G, Basar E, Yalug K, Aker T. Posttraumatic stress disorder and risk factors in parents of children with a cancer diagnosis. Pediatr Hematol Oncol. 2008 Jan-Feb;25(1):27-38. PubMed PMID:18231952.
  • Kaytan E, Karadeniz A, Alici S, Fayda M, Kizir A. Unusual metastases from rectal adenocarcinoma; report of two cases with literature review. J BUON. 2002 Oct-Dec;7(4):377-80. PubMed PMID: 17955584.
  • Cakir A, Bilge H, Küçücük H, Okutan M, Fayda EM, Darendeliler E. Effect of field placement errors on dose at junction between divergence matching and half-beam block techniques in craniospinal irradiation. J BUON. 2002 Oct-Dec;7(4):361-4. PubMed PMID: 17955581.
  • Karadeniz A, Saynak M, Kadehci Z, Fayda M, Aksu G, Kocaelli H, Hafiz G. [The results of combined treatment (surgery and postoperative radiotherapy) for tongue cancer and prognostic factors]. Kulak Burun Bogaz Ihtis Derg. 2007;17(1):1-6. Turkish. PubMed PMID: 17483603.
  • Aksu G, Karadeniz A, Fayda M, Dizdaroglu F. The effect of epithelial and myoepithelial differentiations on survival in a parotid gland undifferentiated carcinoma: case report and review of the literature. J BUON. 2003 Oct-Dec;8(4):389-92. PubMed PMID: 17472283.
  • Cakir A, Bilge H, Dadaşbilge AK, Fayda EM, Okutan M, Küçücük H. Do collimator angle setup errors cause dose inhomogeneity at the junction zone during craniospinal irradiation? A phantom study. J BUON. 2004 Apr-Jun;9(2):193-6. PubMed PMID: 17415814.
  • Aksu G, Ulutin C, Fayda M, Saynak M. Cerebellar and multiple spinal hemangioblastomas and intraventricular meningioma managed with subtotal resection and external beam radiotherapy; report of a case with literature review. J BUON. 2005 Jul-Sep;10(3):405-9. PubMed PMID: 17357198.
  • Saynak M, Aksu G, Fayda M, Kaytan E, Oral E, Gurocak S, Kizir A, Karadeniz A. The results of concomitant and sequential chemoradiotherapy with cisplatin and etoposide in patients with locally advanced non-small cell lung cancer. J BUON. 2005 Apr-Jun;10(2):213-8. PubMed PMID: 17343331.
  • Arslan M, Karadeniz AN, Aksu G, Güveli M, Fayda M, Doğan AK, Akyüz F. Postoperative hypofractionated radiotherapy in glioblastoma multiforme. J BUON. 2006 Jan-Mar;11(1):39-42. PubMed PMID: 17318950.
  • Ulutin C, Cetinayak O, Aksu G, Fayda M, Ataergin S, Beyzadeoğlu M. Malignant peripheral primitive neuroectodermal (pPNET) of tongue. Auris Nasus Larynx. 2007 Mar;34(1):115-8. Epub 2007 Jan 19. Review. PubMed PMID: 17240098.
  • Ulutin C, Fayda M, Aksu G, Cetinayak O, Kuzhan O, Ors F, Beyzadeoglu M. Primary glioblastoma multiforme in younger patients: a single-institution experience. Tumori. 2006 Sep-Oct;92(5):407-11. PubMed PMID: 17168433.
  • Aksu G, Kucucuk S, Fayda M, Saynak M, Baskaya S, Saip P, Ozturk N, Aslay I. The role of postoperative radiotherapy in node negative breast cancer patients with pT3-T4 disease. Eur J Surg Oncol. 2007 Apr;33(3):285-93. Epub 2006 Dec 4. PubMed PMID: 17145158.
  • Ulutin HC, Aksu G, Fayda M, Kuzhan O, Tahmaz L, Beyzadeoglu M. The value of postoperative radiotherapy in renal cell carcinoma: a single-institution experience. Tumori. 2006 May-Jun;92(3):202-6. PubMed PMID: 16869236.
  • Bakkal BH, Kaya B, Berberoglu S, Aksu G, Sayin MY, Altundag MB, Fayda M. The efficiency of different chemoradiotherapy regimens in patients with paediatric nasopharynx cancer: review of 46 cases. Int J Clin Pract. 2007 Jan;61(1):52-61. Epub 2006 Jun 19. PubMed PMID: 16787436.
  • Aksu G, Fayda M, Saynak M, Tore G, Alatli C. Is early postradiation dysplasia almost associated with poor prognosis? A case report and review of the literature. Int J Gynecol Cancer. 2006 Mar-Apr;16(2):934-6. PubMed PMID: 16681791.
  • Aksu G, Karadeniz A, Saynak M, Fayda M, Kadehci Z, Kocaelli H. Treatment results and prognostic factors in oral tongue cancer: analysis of 80 patients. Int J Oral Maxillofac Surg. 2006 Jun;35(6):506-13. Epub 2006 Feb 28. PubMed PMID:16503396.
  • Ulutin HC, Fayda EM. Retrospective, single-institution study on patterns of failure in male breast carcinoma patients after external beam radiotherapy. Tumori. 2005 Sep-Oct;91(5):443; author reply 443. PubMed PMID: 16459646.
  • Agaoglu FY, Fayda M, Dizdar Y, Basaran M, Yazar A, Darendeliler E. Primary uterine lymphoma: case report and literature review. Aust N Z J Obstet Gynaecol. 2005 Feb;45(1):88-9. PubMed PMID: 15730377.
  • Aksu G, Fayda M, Sakar B, Kapran Y. Colon cancer with isolated metastasis to the kidney at the time of initial diagnosis. Int J Gastrointest Cancer. 2003;34(2-3):73-7. PubMed PMID: 15361638.
  • TROD (Turkish Radiation Oncology Association)
  • ASCO (American Soicety of Clinical Oncology)
  • ASTRO (American Society for Radiation Oncology)
  • ESTRO (European Society for Radiation Oncology)
  • Neuro-Oncology Association
  • Prof. Dr. Nijad Bilge Prize 2016 is given on his study titled “Do circulating long non-coding RNAs (lncRNAs) (LincRNA-p21, GAS 5, HOTAIR) predict the treatment response in patients with head and neck cancer treated with chemoradiotherapy?”

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