IVF treatment is a method that we apply to people who cannot have children due to reasons such as unexplained infertility, low sperm quality, sperm blockage in the tubes, overweight, advanced age. According to this treatment method, eggs taken from the woman and sperm known as male reproductive cells are collected and fertilized in a laboratory environment and placed in the uterus of the mother.
As in all medical processes, Liv Hospital offers couples the most advanced treatment options in reproductive health. Quality standards established in line with international criteria provide services with unlimited support, high clinical experience and latest treatment protocols.
The Liv Hospital IVF unit, which consists of specialized physicians and aims at personalized treatment, decides the most appropriate treatment option together with its guests. Following the first interview, ovulation induction (regulation of ovulation), surgical intervention, intrauterine insemination (vaccination) or IVF-ICSI (in vitro fertilization) are provided for the cause of infertility. Psychological support is also supported.
In vitro fertilization is a preferred treatment method for couples or individuals who cannot have children with natural methods. Generally, reasons such as advanced age, infertility of unknown origin, infection, sperm quality or lack, obesity can prevent being a mother or father. With the in vitro fertilization method, which is frequently preferred today, female or male reproductive cells are brought together in a laboratory environment and the fertilized egg obtained is placed in the mother's womb. As a result of this method, which is also called the artificial insemination technique, pregnancy begins with the successful attachment of the embryo in the mother's womb.
What is a test tube baby?
Liv Hospital IVF Unit offers advanced treatment options to families who want to have a child with its specialist physicians, advanced treatment protocols and high clinical experience. It provides medical, surgical and psychological support to all patients from the first interview to the last stage of treatment. In the IVF clinic, which complies with international health criteria, it achieves a high rate of success and removes the obstacles for couples to have a child.
As Liv Hospital IVF unit, the IVF treatment methods we prefer for our patients;
What are the IVF treatment methods applied in our clinic?
- Vaccination: It is the production of eggs by the mother-to-be with needle or pill-shaped methods and the placement of sperm directly into the uterus by selecting the eggs before cracking. The age criterion sought for the application was accepted as 38. At the same time, the expectant mother should have a normal ovarian reserve and the sperm mobility of the man should be at a certain level.
- IVF: IVF treatment, known as the standard in vitro fertilization method, is the process of combining the eggs taken from the woman and the sperms taken from the man in a special laboratory. It is one of the most preferred methods of conceiving a baby.
- ICSI: The ICSI method, also called microinjection, is the injection of sperm into each mature egg collected and the creation of an embryo.
- TESE: TESE (semen analysis) method is used in cases where sperm cells cannot be found and are called azoospermia. In this method, aspiration method can also be used to obtain sperm. The procedure performed under anaesthesia is more sensitive than multiple biopsy applications. The success rate is quite high.
What is Infertility?It is called infertility (infertility) in case of no pregnancy at the end of one year despite unprotected and adequate frequency. 85 percent of the couples in one year, 93 percent in two years of pregnancy. The remaining group is considered infertile and needs help-assisted reproductive techniques. Infertility problem can be seen in 15-20% of society.,
Infertility CausesIn today's technology, 85-90% of infertile couples can detect the factor that prevents pregnancy. Approximately 40 percent of them are women and 40 percent of them are male. In the remaining 20 percent group all parameters are normal; So in this group of couples in the current information is not handled by a reason. This is called "infertile inexplicable reason".
The most important factor affecting success in IVF treatment is female age and female egg reserve. Especially in women above the age of 38, the number of eggs in the reservoir, the quality of which begins to decrease significantly; Even over 40 years of age with the baby in the pregnancy rates fall to 30 percent. According to the currently accepted criteria; In women 45 years of age (with some exceptions), the ceiling is considered as age to be able to achieve pregnancy with treatments.
Some of the women-related problems may lead to the necessity of surgery prior to the IVF treatment, while some problems may alter the treatment protocol. For example, congenital or later acquired disorders in the uterus can be surgically corrected first and then treatment is started, or if the woman has less or greater than expected age according to the age of the ovarian reserve, treatment protocols and medication doses are adjusted accordingly.
Closed tubes, hydrosalpenx (inflammation of tubes)
- Ovulation disorders, polycystic ovarian syndrome
- Uterine and cervical disorders, the presence of a curtain in the uterus
- Hormonal and metabolic problems, thyroid dysfunction
- Endometriosis and chocolate cysts
- Abdominal membrane problems, adhesions due to previous operations
- Advanced woman age
Men-based causesIn 30-40% of infertile couples, the only cause is male. In 10-15% of cases, women are accompanied by problems. Semen analysis is the most basic and guiding step in infertility studies.
- Problems in sperm count or sperm movement
- Sperm Disorders
- Absence of sperm (Azospermia)
- Blockage in sperm carrier channels, absence of channels
- Erectile or ejaculation problems
- Hormonal causes
- Genetic reasons
There are two possible causes of azoospermia.
- Due to occlusion: In this case, there is no problem in the production of sperm of the male, although there is a congestion caused by the reasons such as surgery or infection in the vaginal path between the testis and the penis, or the sperms cannot pass from the testicle to the male due to the lack of congenital paths.
- Non-clogging: This is the more common group. Although males often do not have a disorder in this type of males, the problem is inadequate sperm production. The cause may also be hormonal, genetic or previous infection. In most cases, there is no reason to explain the situation.
IVF Treatment Steps
- Evaluation of infertile couple, gynecological and urological examinations
- Selective planning of treatment method
- Development of eggs by drug stimulation (Ovulation induction)
- Egg collection under anesthesia (OPU procedure)
- Fertilization of eggs with sperm (ICSI)
- Embryo transfer
Tube Baby Current TechniquesAssisted Hatching
It is the process of shaving and scratching the surrounding membrane to facilitate attachment of the embryo to be transferred to the inner wall of the uterus. Implantation is believed to sometimes increase the rate of attachment.
PGD (Preimplantation Genetic Diagnosis)
The embryos performed on the third or fifth day of development of the embryos are biopsied and the process of detecting abnormal or disease-bearing embryos and transferring double normal embryos. Couples who are carriers of a known genetic disease, recurrent miscarriages, recurrent tube infant failure, the detection of the tissue type of embryos (HLA determination) for the treatment of the sibling with blood disease are applied on grounds such as advanced age. Thanks to this process, the embryos with healthy chromosomes are transferred to increase the live birth rate.
Sperm Selection with IMSI and Double Fracture Method
The number of mature eggs obtained from thousands of sperm cells in the sample of semen taken from men in tube infant operations is chosen and used. This choice is usually based on the experience of the embryologist. In IMSI method, more image enlargement is provided than classical microscopes and more accurate evaluation of sperm structure is provided. Thus, better, quality sperm selection is provided. This method may aid in the selection of better quality sperm in cases of severe male infertility, unexplained in vitro failure and low quality embryo production.
Hysteroscopy and Laparoscopy
In hysteroscopy, which is the process of imaging the uterus into the uterus with an illuminated camera system, problems such as structural defects of the uterus (curtain, double uterus), myomas, polyps, adhesion (synechia) can be detected and treatments can be performed at the same time. Performing hysteroscopy may increase the success of the gynecology if the problem detected before the IVF procedure is uterine origin or if a diagnosis of recurrent tube infant is diagnosed.
Laparoscopy is the process of imaging the abdomen with a light camera system. Generally surgical treatment of ovarian cysts, opening of the adhesions due to the surgeries performed, surgical treatment of the fibroids located outside the uterus and evaluation of the tubes are performed with this method. In fact, almost all surgeries that are now open can be done by laparoscopy. It is known that removal of the tubes by laparoscopic method may increase the success of the pregnancy in the case of "hydrosalpenks" where the inside of the tubes are filled with liquid, which can adversely affect the success of the IVF.
Embryo Freezing, Storage and Thaw
The embryos can be frozen by special methods at any time between the second day and the fifth day of development and then stored in gün -196 gün degree nitrogen nitrogen. After embryo transfer, the embryos that are increased and of good quality are then frozen for use in the case of sibling or in case of treatment failure.
Ovarian hypersitumation is called OHSS when the ovaries are over-responding to the drugs used and the fluid is collected in the mother's body. Modern IVF treatments have specific drug treatment protocols for such risky patients. In addition, the embryos formed for the purpose of preventing OHSS are all frozen and stored for later transfer. Modern methods of freeze-thawing embryos reduce the risk of this problem to zero without affecting embryo quality.
What is the success rate in IVF treatment?There are many criteria that affect the success rate of IVF treatment. This rate is estimated to be 55-60% for women under the age of 30 and 15-20% for women over the age of 40. Especially the decrease in embryo quality due to advancing age has been accepted as an important reason affecting the chance of success.
Embryo transfer is a very short and simple procedure. In the first step of the procedure, a plastic catheter is placed in the cervix by a specialist doctor. The resulting embryo is successfully transferred to the mother's womb with this catheter. With egg-developing needles, more embryos than desired can be obtained in the pre-procedure process. In such a case, embryos that are not transferred can also be frozen and stored
How are embryos placed in the uterus after the eggs are fertilized?